| 2019-01-13 12:05:00January 13, 2019 | Los Angeles Chargers | 28 - 41 | New England Patriots | 12:05:0012:05 pm |
| 2019-01-06 12:05:00January 6, 2019 | Los Angeles Chargers | 23 - 17 | Baltimore Ravens | 12:05:0012:05 pm |
| 2018-12-30 15:25:00December 30, 2018 | Los Angeles Chargers | 23 - 9 | Denver Broncos | 15:25:003:25 pm |
| 2018-12-22 19:20:00December 22, 2018 | Baltimore Ravens | 22 - 10 | Los Angeles Chargers | 19:20:007:20 pm |
| 2018-12-13 19:20:00December 13, 2018 | Los Angeles Chargers | 29 - 28 | Kansas City Chiefs | 19:20:007:20 pm |
| 2018-12-09 15:05:00December 9, 2018 | Cincinnati Bengals | 21 - 26 | Los Angeles Chargers | 15:05:003:05 pm |
| 2018-12-02 19:20:00December 2, 2018 | Los Angeles Chargers | 33 - 30 | Pittsburgh Steelers | 19:20:007:20 pm |
| 2018-11-25 15:05:00November 25, 2018 | Arizona Cardinals | 10 - 45 | Los Angeles Chargers | 15:05:003:05 pm |
| 2018-11-18 15:05:00November 18, 2018 | Denver Broncos | 23 - 22 | Los Angeles Chargers | 15:05:003:05 pm |
| 2018-11-11 15:05:00November 11, 2018 | Los Angeles Chargers | 20 - 6 | Oakland Raiders | 15:05:003:05 pm |
| 2018-11-04 15:05:00November 4, 2018 | Los Angeles Chargers | 25 - 17 | Seattle Seahawks | 15:05:003:05 pm |
| 2018-10-21 08:30:00October 21, 2018 | Tennessee Titans | 19 - 20 | Los Angeles Chargers | 08:30:008:30 am |
| 2018-10-13 12:00:00October 13, 2018 | Los Angeles Chargers | 38 - 14 | Cleveland Browns | 12:00:0012:00 pm |
| 2018-10-07 15:05:00October 7, 2018 | Oakland Raiders | 10 - 26 | Los Angeles Chargers | 15:05:003:05 pm |
| 2018-09-30 15:25:00September 30, 2018 | San Francisco 49ers | 27 - 29 | Los Angeles Chargers | 15:25:003:25 pm |
| 2018-09-23 15:05:00September 23, 2018 | Los Angeles Chargers | 23 - 35 | Los Angeles Rams | 15:05:003:05 pm |
| 2018-09-16 12:00:00September 16, 2018 | Los Angeles Chargers | 31 - 20 | Buffalo Bills | 12:00:0012:00 pm |
| 2018-09-09 15:05:00September 9, 2018 | Kansas City Chiefs | 38 - 28 | Los Angeles Chargers | 15:05:003:05 pm |